There are many ways to prepare spaghetti squash but this video takes your through a quick and easy method. First, pierce your squash with a fork and microwave it on a microwave-safe dish. Note that you should microwave the squash for an average of five minutes per pound. In this video, the cook is using a 3 pound squash so she microwaves her squash for 15 minutes. After it's done cooking, allow the squash to cool and cut it in half to remove the seeds. Now you are left with the squash flesh. Using a fork, scrape at the flesh and store it in a container. The spaghetti squash is a low calorie food item and you can use it for various healthy meals.